An LDH (lactate dehydrogenase) test measures the amount of LDH in your blood or other body fluid to check for tissue damage. While it's normal to have some LDH in your blood or body fluids, when tissues in your body experience damage or injury, they release excess LDH into your bloodstream or other body fluids.
What is Lactate? Lactate is a bi-product constantly produced in the body during normal metabolism and exercise. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal which is governed by a number of factors.
Blood lactate levels are elevated in diseases affecting energy metabolism. Lactate is an intermediate product produced in the breakdown of glucose. Its elevation reflects either overuse of the system or a direct block (such as block by pyruvate dehydrogenase or pyruvate carboxylase). Disorders in mitochondrial energy metabolism or fatty acid
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Lactic acid, also called lactate, is a product of pyruvate metabolism under anaerobic conditions. The tissues that produce most lactic acid are the muscle cells and red blood cells. An elevated lactate level and a pH equal to or less than 7.35 cause lactic acidosis.
Blood lactate levels represent the balance between lactate production and lactate metabolism. The liver is responsible for the major part of lactate metabolism. Inadequate oxygen delivery and tissue hypoxia, irrespective of the underlying etiology, results in increased lactate generation.
The levels of blood lactate and fibrinogen may represent the severity of children with traumatic brain injury and may be risk factors for poor prognosis of children with traumatic brain injury. Traumatic brain injury (TBI) is a significant cause of morbidity and mortality in pediatric patients, leading to long-term physical, cognitive, and
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what is lactate in blood